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MCM7 antibody [47DC141]

Anti-MCM7 antibody [47DC141] used in IHC (Paraffin sections) (IHC-P). GTX73948

Cat. No. GTX73948

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 47DC141

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
1 ml ($789)
See all MCM7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50‐1:100

Note :

IHC-P
Recommendations for antigen retrieval : Citrate Buffer pH 6.0 at room temperature for 30 mins.
Not tested in other applications.

Calculated MW

81 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

BALB/C mice were injected with recombinant human cdc47 protein.

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_383767

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

minichromosome maintenance complex component 7 , CDC47 , MCM2 , P1.1-MCM3 , P1CDC47 , P85MCM , PNAS146 , PPP1R104

Cellular Localization

Nucleus

Background

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MCM7 antibody [47DC141] used in IHC (Paraffin sections) (IHC-P). GTX73948

GTX73948 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX73948 MCM7 antibody [47DC141].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 789