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MCP1 / CCL2 antibody [S101]

Cat No. GTX18678

Host

Mouse

Clonality

Monoclonal

Clone Name

S101

Isotype

IgG1

Application

WB, ELISA, Neutralizing/Inhibition

Reactivity

Human, Rabbit
Package
250 μg ($379)

APPLICATION

Application Note

ELISA: Use at an assay dependent dilution. Neut: Use at a concentration of 0.5 μg/ml. WB: Use at a concentration of 0.1 - 5 μg/ml. At a concentration of 0.1 - 1.0 μg/mL the antibody will allow visualization of 0.1 μg/lane of human MCP1. Concentration of 5.0 μg/mL will allow visualization of 50 μg/lane of rabbit MCP1. Predicted molecular weight: 11 kDa. Optimal dilutions/concentrations should be determined by the end user.

Calculated MW

11 kDa. ( Note )

Product Note

GTX18678 reacts with natural and recombinant human MCP1. It does not react with human interleukin 8 (IL8) and other human cytokines tested such as interleukin 1 beta (IL1 beta), serum amyloid A (SAA) and epidermal growth factor (EGF).

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.2

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full length protein (Human).

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C motif chemokine ligand 2 , GDCF-2 , HC11 , HSMCR30 , MCAF , MCP-1 , MCP1 , SCYA2 , SMC-CF

Cellular Localization

Secreted

Background

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2013]

Database

Research Area

REFERENCE

There are currently no references for MCP1 / CCL2 antibody [S101] (GTX18678). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MCP1 / CCL2 antibody [S101] (GTX18678). Be the first to share your experience with this product.
SDS
PBS.pdf
Package List Price ($)
$ 379
Custom Conjugations