Phosphate buffered saline, pH 7.2, containing 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
1 mg/ml (Please refer to the vial label for the specific concentration.)
Recombinant fragment - amino acids 1-73 of rat MCP-1 (N-terminal)
Protein A affinity purified
From polyclonal serum
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
C-C Motif Chemokine Ligand 2,Mcp-1,Scya2,Sigje,Ccl2
Rat MCP-1/JE (monocyte chemoattracctant protein-1) is an 148 amino acid CC chemokine with a NH2- terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con A-stimulated rat spleen cDNA library1. This rat MCP-1/JE is 49 amino acid longer than human MCP-1 at 3’- end. This 3’-end is a serine and threonine rich zone, which is probably responsible for the extensive O- glycosylation and which explains for the higher molecular weight (25 kDa)2. In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophils. MCP- 1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli.