Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1-2 μg/ml |
2.0 μg/ml |
1-4 μg/ml |
Not tested in other applications.
Calculated MW
Product Note
Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
recombinant human MCP-2 expressed in E. coli.
Purification
Purified immunoglobulin
Conjugation
Unconjugated
RRID
AB_373987
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
C-C motif chemokine ligand 8 , HC14 , MCP-2 , MCP2 , SCYA10 , SCYA8
Cellular Localization
Secreted
Background
MCP2 and MCP3 are members of the C-C, or beta chemokine class. Other chemokines in this group include C10, Eotaxin, HCC1, I309, JE, MCP1, MIP1 alpha, MIP1 beta and RANTES. These chemokines act primarily as chemoattractants and antibody does not cross-react with other activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. MCP2 and MCP3 were originally identified as monocyte chemotactic proteins produced by human MG63 osteosacrcoma cells. MCP2 and MCP3 are approximately 9 kD polypeptides of 76 amino acids. MCP2 shares 62% amino acid sequence homology with MCP1, MCP3 shares 71% homology with MCP1, and MCP2 shares 58% homology with MCP3.
Database
Research Area