GeneTex
United States (US)

MCP2 antibody [35509.11]

Cat No. GTX10391

Host Mouse
Clonality Monoclonal
Clone Name 35509.11
Isotype IgG1
Application WB, ELISA, Neut
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-2 μg/ml
ELISA 2.0 μg/ml
Neut 1-4 μg/ml
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Specificity/Sensitivity

Neutralizes the biological activity of recombinant human MCP-2. Shows <20% cross-reactivity with recombinant human MCP-1 and recombinant mouse MIP-1α.
PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

recombinant human MCP-2 expressed in E. coli.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

C-C Motif Chemokine Ligand 8,Hc14,Mcp-2,Mcp2,Scya10,Scya8,Ccl8

Background

MCP2 and MCP3 are members of the C-C, or beta chemokine class. Other chemokines in this group include C10, Eotaxin, HCC1, I309, JE, MCP1, MIP1 alpha, MIP1 beta and RANTES. These chemokines act primarily as chemoattractants and antibody does not cross-react with other activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. MCP2 and MCP3 were originally identified as monocyte chemotactic proteins produced by human MG63 osteosacrcoma cells. MCP2 and MCP3 are approximately 9 kD polypeptides of 76 amino acids. MCP2 shares 62% amino acid sequence homology with MCP1, MCP3 shares 71% homology with MCP1, and MCP2 shares 58% homology with MCP3.

Database

Research Area

Package List Price ($)
$ 289