*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The antibody may be used for neutralization, localization and detection of human MCP-2. It will not neutralize recombinant human MCP-1 or MCP-3, or recombinant mouse JE. The antibody shows <40% cross-reactivity with recombinant human HCC-1, <10% cross-reactivity with recombinant human eotaxin, and <5% cross-reactivity with recombinant human MCP-1.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
Purified E. coli-derived recombinant human MCP2.
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
C-C Motif Chemokine Ligand 8,Hc14,Mcp-2,Mcp2,Scya10,Scya8,Ccl8
MCP2 and MCP3 are two recently identified monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and MCP3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. MCP3 also shares 58% amino acid identity with MCP2. Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.