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MCP2 antibody

Cat No. GTX10392

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, ELISA, Neutralizing/Inhibition

Reactivity

Human
Package
25 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Product Note

The antibody may be used for neutralization, localization and detection of human MCP-2. It will not neutralize recombinant human MCP-1 or MCP-3, or recombinant mouse JE. The antibody shows <40% cross-reactivity with recombinant human HCC-1, <10% cross-reactivity with recombinant human eotaxin, and <5% cross-reactivity with recombinant human MCP-1.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified E. coli-derived recombinant human MCP2.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

C-C motif chemokine ligand 8 , HC14 , MCP-2 , MCP2 , SCYA10 , SCYA8

Cellular Localization

Secreted

Background

MCP2 and MCP3 are two recently identified monocyte chemotactic proteins produced by human MG63 osteosarcoma cells. Both MCP2 and MCP3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP1. MCP3 also shares 58% amino acid identity with MCP2. Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 319