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MCP3 antibody [36320.11]

Cat. No. GTX10589

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 36320.11

Isotype

 IgG1

Application

 WB, ELISA, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all MCP3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ELISA Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

11 kDa. ( Note )

Product Note

Neutralizes the biological activity of recombinant human MCP-3. Does not cross-react with recombinant human MCP-1 or MCP-2.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

recombinant human MCP-3.

Purification

Purified immunoglobulin

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

C-C motif chemokine ligand 7 , FIC , MARC , MCP-3 , MCP3 , NC28 , SCYA6 , SCYA7

Cellular Localization

Secreted

Background

MCP2 and MCP3 are members of the C-C, or chemokine class. Other chemokines in this group include C10, Eotaxin, HCC1, I309, JE, MCP1, MIP1 and RANTES. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. MCP2 and MCP3 were originally identified as monocyte chemotactic proteins produced by human MG63 osteosacrcoma cells. MCP2 and MCP3 are approximately 9 kD polypeptides of 76 amino acids. MCP2 shares 62% amino acid sequence homology with MCP1, MCP3 shares 71% homology with MCP1, and MCP2 shares 58% homology with MCP3.

Database

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399