APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:300-1000 |
| 1:50-400 |
| 1:20-100 |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
1% BSA, 50% Glycerol
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide derived from human MCT8(118-143).
Purification
Protein A purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
solute carrier family 16 member 2 , AHDS , DXS128 , DXS128E , MCT 7 , MCT 8 , MCT7 , MCT8 , MRX22 , XPCT
Cellular Localization
Cell membrane
Background
This gene encodes an integral membrane protein that functions as a transporter of thyroid hormone. The encoded protein facilitates the cellular importation of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine (T2). This gene is expressed in many tissues and likely plays an important role in the development of the central nervous system. Loss of function mutations in this gene are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes. This gene is subject to X-chromosome inactivation. Mutations in this gene are the cause of Allan-Herndon-Dudley syndrome. [provided by RefSeq, Mar 2012]
Database
Research Area
DATA IMAGES
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GTX51095 IHC-P Image
IHC-P analysis of rat brain tissue using GTX51095 MCT8 antibody.
Dilution : 1:200
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GTX51095 WB Image
WB analysis of mouse heart lysate using GTX51095 MCT8 antibody.
Dilution : 1:1000
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GTX51095 FACS Image
FACS analysis of H9C2 cells using GTX51095 MCT8 antibody.
Green : Primary antibody
Blue : Unstained cells
Orange : Isotype control
Light blue : Secondary antibody only
Antibody amount : 3μg
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GTX51095 IHC-P Image
IHC-P analysis of human kidney tissue using GTX51095 MCT8 antibody.
Antigen retrieval : Boiling in sodium citrate buffer (pH6) for 15min
Dilution : 1:200
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GTX51095 FACS Image
FACS analysis of mouse cells using GTX51095 MCT8 antibody.
Green : Primary antibody
Blue : Unstained cells
Dilution : 1:100
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REFERENCE
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REVIEW
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