*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
The monoclonal antibody 18H10 reacts with MD-2. However, it does not react with sMD-2. In addition, the monoclonal antibody 18H10 is able to inhibit bacterial binding to MD-2.
0.2μm-filtered PBS, 0.1% BSA
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
100 μg/ml (Please refer to the vial label for the specific concentration.)
TLR4/MD-2 expressing CHO cells/ chimeric TLR4/MD-2 fusion protein
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
ESOP1,LY96,MD2,ly96,lymphocyte antigen 96,MD-2
This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2010]