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MED23 antibody

Anti-MED23 antibody used in IHC (Paraffin sections) (IHC-P). GTX87948
Anti-MED23 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87948

Cat. No. GTX87948

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 ICC/IF, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MED23 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
ICC/IF 1:100~1:500
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

156 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human MED23 (1-50).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

ARC130 , CRSP130 , CRSP133 , CRSP3 , DRIP130 , MED23 , MRT18 , SUR2 , mediator complex subunit 23

Cellular Localization

Nucleus

Background

The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2012]

Database

Research Area

DATA IMAGES

Anti-MED23 antibody used in IHC (Paraffin sections) (IHC-P). GTX87948

GTX87948 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX87948 MED23 antibody. The picture on the right is blocked with the synthesized peptide.

Anti-MED23 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX87948

GTX87948 ICC/IF Image

ICC/IF analysis of A549 cells using GTX87948 MED23 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399