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MEK2 antibody [7F5]

Anti-MEK2 antibody [7F5] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83358
Anti-MEK2 antibody [7F5] used in Western Blot (WB). GTX83358
Anti-MEK2 antibody [7F5] used in Flow cytometry (FACS). GTX83358

Cat. No. GTX83358

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7F5

Isotype

 IgG1

Application

 WB, ICC/IF, FACS, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MEK2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
ICC/IF 1/200 - 1/1000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

44 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human MAP2K2 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mitogen-activated protein kinase kinase 2 , CFC4 , MAPKK2 , MEK2 , MKK2 , PRKMK2

Cellular Localization

Cytoplasm,Membrane

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MEK2 antibody [7F5] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX83358

GTX83358 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX83358 MEK2 antibody [7F5].
Green : MEK2
Blue: DRAQ5 fluorescent DNA dye
Red: Actin filaments

Anti-MEK2 antibody [7F5] used in Western Blot (WB). GTX83358

GTX83358 WB Image

WB analysis of PC-12 (1), Jurkat (2), HeLa (3) and NIH3T3 (4) cell lysate using GTX83358 MEK2 antibody [7F5].

Anti-MEK2 antibody [7F5] used in Flow cytometry (FACS). GTX83358

GTX83358 FACS Image

FACS analysis of HeLa cells using GTX83358 MEK2 antibody [7F5].
Green : MEK2
Purple : negative control

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399