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MEK2 antibody

Anti-MEK2 antibody used in Western Blot (WB). GTX35223
Anti-MEK2 antibody used in Western Blot (WB). GTX35223

Cat No. GTX35223

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
Package
100 μl ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

44 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% glycerol, 0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP2K2 (NP_109587.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Mitogen-Activated Protein Kinase Kinase 2,Cfc4,Mapkk2,Mek2,Mkk2,Prkmk2,Map2K2

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008]

Research Area

DATA IMAGES
Anti-MEK2 antibody used in Western Blot (WB). GTX35223

GTX35223 WB Image

WB analysis of wild type and MEK2 knockout cell lysate using GTX35223 MEK2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-MEK2 antibody used in Western Blot (WB). GTX35223

GTX35223 WB Image

WB analysis of various samples using GTX35223 MEK2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE
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Package List Price ($)
$ 329