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MEK6 antibody [3H12B9]

Anti-MEK6 antibody [3H12B9] used in IHC (Paraffin sections) (IHC-P). GTX60397
Anti-MEK6 antibody [3H12B9] used in Western Blot (WB). GTX60397
Anti-MEK6 antibody [3H12B9] used in ELISA (ELISA). GTX60397

Cat. No. GTX60397

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 3H12B9

Isotype

 IgG1

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse
Package
100 μl ($409)
See all MEK6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
IHC-P 1/200 - 1/1000
ELISA 1/10000
Not tested in other applications.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human MEK6 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mitogen-activated protein kinase kinase 6 , MAPKK6 , MEK6 , MKK6 , PRKMK6 , SAPKK-3 , SAPKK3

Cellular Localization

Nucleus,Cytoplasm,Cytoplasm, cytoskeleton

Background

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MEK6 antibody [3H12B9] used in IHC (Paraffin sections) (IHC-P). GTX60397

GTX60397 IHC-P Image

IHC-P analysis of ovarian cancer (left) and kidney cancer (right) using GTX60397 MEK6 antibody [3H12B9].

Anti-MEK6 antibody [3H12B9] used in Western Blot (WB). GTX60397

GTX60397 WB Image

WB analysis of HepG2 (1), MCF-7 (2) and NIH3T3 (3) cell lysate using GTX60397 MEK6 antibody [3H12B9].

Anti-MEK6 antibody [3H12B9] used in ELISA (ELISA). GTX60397

GTX60397 ELISA Image

ELISA analysis of antigen using GTX60397 MEK6 antibody [3H12B9].
Red : Control antigen 100ng
Purple : Antigen 10ng
Green : Antigen 50ng
Blue : Antigen 100ng

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409