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MEK6 antibody [EP558Y], C-term

Anti-MEK6 antibody [EP558Y], C-term used in Western Blot (WB). GTX61432
Anti-MEK6 antibody [EP558Y], C-term used in IHC (Paraffin sections) (IHC-P). GTX61432

Cat. No. GTX61432

Host

 Rabbit

Clonality

 Monoclonal

Clone Name

 EP558Y

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MEK6 products

APPLICATION

Application Note

Recommended Starting Dilutions:
For WB: Use at a dilution of 1:10,000
For IHC: Use at a dilution of 1:100 - 250.
Optimal working dilution for a specific application should be determined by the investigator.

Calculated MW

37 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

50mM Tris-Glycine (pH7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to residues in the C-term of human MEK6 was used as immunogen.

Purification

Tissue culture supernatant

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.

TARGET

Synonyms

mitogen-activated protein kinase kinase 6 , MAPKK6 , MEK6 , MKK6 , PRKMK6 , SAPKK-3 , SAPKK3

Cellular Localization

Nucleus , Cytoplasm , Cytoplasm, cytoskeleton

Background

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MEK6 antibody [EP558Y], C-term used in Western Blot (WB). GTX61432

GTX61432 WB Image

A. Western blot analysis on Hela cell lysate using anti-MKK6 RabMAb (cat. # GTX61432) dilution 1:10000.

Anti-MEK6 antibody [EP558Y], C-term used in IHC (Paraffin sections) (IHC-P). GTX61432

GTX61432 IHC-P Image

B. Immunohistochemical analysis of paraffin-embedded human heart muscle using anti-MKK6 RabMAb (cat # GTX61432).

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399