GeneTex
United States (US)

MEK7 antibody

GTX54352_20180530_ICCIF_18121411_990.jpg
GTX54352_20180530_WB_18121411_268.jpg

Cat No. GTX54352

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

47 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 1-250 of human MAP2K7 (NP_660186.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

JNKK2 Antibody , PRKMK7 Antibody , MAPKK7 Antibody , MAP2K7 Antibody , MKK7 Antibody , SAPKK4 Antibody

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX54352_20180530_ICCIF_18121411_990.jpg

GTX54352 ICC/IF Image

ICC/IF analysis of U2OS cell using GTX54352 MEK7 antibody.
Blue : DAPI

GTX54352_20180530_WB_18121411_268.jpg

GTX54352 WB Image

WB analysis of various samples using GTX54352 MEK7 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319