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MEK7 (phospho Ser271/Thr275) antibody

Anti-MEK7 (phospho Ser271/Thr275) antibody used in Western Blot (WB). GTX24762

Cat. No. GTX24762

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human, Rat
Package
50 μl ($399)
See all MEK7 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-1 μg/ml
Not tested in other applications.

Calculated MW

47 kDa. ( Note )

Product Note

This antibody does not react with other MEK isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 1mg/ml BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against a chemically synthesized phosphopeptide derived from a region of human MEK7 that contains serine 271 and threonine 275.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mitogen-activated protein kinase kinase 7 , JNKK2 , MAPKK7 , MEK , MEK 7 , MKK7 , PRKMK7 , SAPKK-4 , SAPKK4

Cellular Localization

Nucleus,Cytoplasm

Background

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Database

Research Area

DATA IMAGES

Anti-MEK7 (phospho Ser271/Thr275) antibody used in Western Blot (WB). GTX24762

GTX24762 WB Image

WB analysis of background extracts with GST-tagged fusion protein expressing MEK7 using GTX24762 MEK7 (phospho Ser271/Thr275) antibody.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399