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METAP2 antibody, N-term

Anti-METAP2 antibody, N-term used in Western Blot (WB). GTX45796
Anti-METAP2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX45796
Anti-METAP2 antibody, N-term used in Western Blot (WB). GTX45796

Cat. No. GTX45796

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
50 μg ($399)
See all METAP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.2-2.5 ug/ml
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Positive Control

human fetal brain , Jurkat

PROPERTIES

Form

Liquid

Buffer

PBS, 2% Sucrose

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human METAP2

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

methionyl aminopeptidase 2 , MAP2 , MNPEP , p67eIF2

Cellular Localization

Cytoplasm

Background

The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]

Database

DATA IMAGES

Anti-METAP2 antibody, N-term used in Western Blot (WB). GTX45796

GTX45796 WB Image

WB analysis of human fetal brain tissue using GTX45796 METAP2 antibody at 0.2-1μg/ml.

Anti-METAP2 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX45796

GTX45796 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX45796 METAP2 antibody at 5μg/ml.

Anti-METAP2 antibody, N-term used in Western Blot (WB). GTX45796

GTX45796 WB Image

WB analysis of Jurkat cells using GTX45796 METAP2 antibody at 1.0μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399