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METTL7A antibody

Anti-METTL7A antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85369
Anti-METTL7A antibody used in Western Blot (WB). GTX85369

Cat. No. GTX85369

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($419)
See all METTL7A products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 μg/mL
ICC/IF 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

28 kDa. ( Note )

Positive Control

MCF7 Cell Slide(GTX25536) , MCF7 Cell Lysate

Product Note

At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MettL7A antibody was raised against a 13 amino acid synthetic peptide near the center of human MettL7A.The immunogen is located within amino acids 130 - 180 of MettL7A.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

methyltransferase like 7A , AAM-B , AAMB

Cellular Localization

Endoplasmic reticulum,Membrane

Background

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis. At least two isoforms of MettL7A are known to exisit. This antibody is predicted to not cross-react with MettL7B.

Database

Research Area

DATA IMAGES

Anti-METTL7A antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX85369

GTX85369 ICC/IF Image

ICC/IF analysis of MCF7 cells using GTX85369 METTL7A antibody.
Working concentration : 2 μg/ml

Anti-METTL7A antibody used in Western Blot (WB). GTX85369

GTX85369 WB Image

WB analysis of MCF7 cell lysate using GTX85369 METTL7A antibody.
Working concentration : 2 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 419