GeneTex
United States (US)

MFN2 antibody

GTX31923_3071_WB_20180221_18121410_263.jpg
GTX31923_1595_IHC-P_20180221_18121410_752.jpg
GTX31923_1594_IHC-P_20180221_18121410_240.jpg

Cat No. GTX31923

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

86 kDa. ( Note )

Positive Control

Human Brain Tissue Lysate(GTX27918)

Specificity/Sensitivity

At least three isoforms of MFN2 are known to exist. MFN2 antibody is predicted to not cross-react with MFN1.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MFN2 antibody was raised against a 17 amino acid peptide near the center of human MFN2.The immunogen is located within amino acids 250 - 300 of MFN2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Mitofusin 2,Cmt2A,Cmt2A2,Cmt2A2A,Cmt2A2B,Cprp1,Hmsn6A,Hsg,Marf,Mfn2

Background

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX31923_3071_WB_20180221_18121410_263.jpg

GTX31923 WB Image

WB analysis of human brain tissue lysate using GTX31923 MFN2 antibody.
Working concentration : 1 μg/ml

GTX31923_1595_IHC-P_20180221_18121410_752.jpg

GTX31923 IHC-P Image

IHC-P analysis of rat brain tissue using GTX31923 MFN2 antibody.
Working concentration : 20 μg/ml

GTX31923_1594_IHC-P_20180221_18121410_240.jpg

GTX31923 IHC-P Image

IHC-P analysis of rat brain tissue using GTX31923 MFN2 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329