APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 - 2 μg/mL |
| 5 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
Human Brain Tissue Lysate(GTX27918)
Product Note
At least three isoforms of MFN2 are known to exist. MFN2 antibody is predicted to not cross-react with MFN1.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
MFN2 antibody was raised against a 17 amino acid peptide near the center of human MFN2.The immunogen is located within amino acids 250 - 300 of MFN2.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
mitofusin 2 , CMT2A , CMT2A2 , CMT2A2A , CMT2A2B , CPRP1 , HMSN6A , HSG , MARF
Cellular Localization
Mitochondrion outer membrane
Background
This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX31923 IHC-P Image
IHC-P analysis of rat brain tissue using GTX31923 MFN2 antibody.
Working concentration : 20 μg/ml
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GTX31923 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31923 MFN2 antibody.
Dilution : 5 μg/ml
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GTX31923 WB Image
WB analysis of human brain tissue lysate using GTX31923 MFN2 antibody.
Working concentration : 1 μg/ml
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GTX31923 IHC-P Image
IHC-P analysis of mouse brain tissue using GTX31923 MFN2 antibody.
Green : Primary antibody
Red : Actin
Blue : DAPI
Dilution : 20 μg/ml
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GTX31923 IHC-P Image
IHC-P analysis of rat brain tissue using GTX31923 MFN2 antibody.
Working concentration : 5 μg/ml
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REFERENCE
There are currently no references for MFN2 antibody (GTX31923). Be the first to share your publications with this product.
REVIEW
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