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MHC Class II RT1B antibody [MRC OX-6] (PE)

Cat. No. GTX76191

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 MRC OX-6

Isotype

 IgG1

Application

 FACS

Reactivity

 Mouse, Rat
Package
1 ml ($319)
See all MHC Class II RT1B products

APPLICATION

Application Note

For FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.

Product Note

Recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells but not peripheral T lymphocytes. This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography.

PROPERTIES

Form

Liquid

Buffer

PBS, BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

Rat Thymocyte membrane glycoprotein

Purification

Protein G affinity purified

Conjugation

Phycoerythrin (PE)

RRID

AB_378744

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Research Area

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319