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MIB1 antibody

Anti-MIB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX53672
Anti-MIB1 antibody used in Western Blot (WB). GTX53672

Cat No. GTX53672

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human
Package
400 μl ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
ICC/IF 1:20-1:100
IHC-P 1:50-1:100
Not tested in other applications.

Calculated MW

110 kDa. ( Note )

Predict Reactivity

Mouse, Zebrafish, Xenopus(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 13-42 amino acids from the N-terminal region of human Mib1/Mindbomb.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

mindbomb E3 ubiquitin protein ligase 1 , DIP-1 , DIP1 , LVNC7 , MIB , ZZANK2 , ZZZ6

Cellular Localization

Cytoplasm,Cell membrane

Background

This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013]

Database

Research Area

DATA IMAGES

Anti-MIB1 antibody used in IHC (Paraffin sections) (IHC-P). GTX53672

GTX53672 IHC-P Image

IHC-P analysis of human hepatocarcinoma using GTX53672 MIB1 antibody.

Anti-MIB1 antibody used in Western Blot (WB). GTX53672

GTX53672 WB Image

WB analysis of K562 cell lysate (35ug/lane) using GTX53672 MIB1 antibody.

REFERENCE

There are currently no references for MIB1 antibody (GTX53672). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf