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MIP1 alpha antibody [11F16]

Cat. No. GTX52606

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 11F16

Isotype

 IgG1

Application

 WB, IHC-P, IHC, Neutralizing/Inhibition

Reactivity

 Human
Package
100 μg ($399)
See all MIP1 alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P Assay dependent
IHC 1:20 - 1:100
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

10 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant CCL-3

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CC motif chemokine ligand 3 , CCL3 , G0S191 , LD78ALPHA , MIP1A , MIP1alpha , SCYA3 , MIP1 alpha , C-C motif chemokine ligand 3

Cellular Localization

Secreted

Background

This locus represents a small inducible cytokine. The encoded protein, also known as macrophage inflammatory protein 1 alpha, plays a role in inflammatory responses through binding to the receptors CCR1, CCR4 and CCR5. Polymorphisms at this locus may be associated with both resistance and susceptibility to infection by human immunodeficiency virus type 1.[provided by RefSeq, Sep 2010]

Database

Research Area

REFERENCE

Application Reference

Sheng D et al. J Immunother Cancer 2022; 10 (5) Ccl3 enhances docetaxel chemosensitivity in breast cancer by triggering proinflammatory macrophage polarization.
Application : IHC-P
Reactivity : Human
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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399