APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:10–1:20 |
Assay dependent |
Note :
IHC-P
High temperature antigen unmasking technique using 1 mM EDTA (pH 8.0). Standard ABC technique.
IHC-Fr
Acetone fixation recommended
|
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human microphthalmia transcription factor, MITF-M isoform.
PROPERTIES
Form
Liquid
Buffer
Tissue culture supernatant
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
Antigen Species
Human
Immunogen
Prokaryotic recombinant protein corresponding to 111 amino acids of the N-terminal region of the MITF-M molecule.
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
melanocyte inducing transcription factor , CMM8 , COMMAD , MI , WS2 , WS2A , bHLHe32
Cellular Localization
Nucleus
Background
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
Database
Research Area
DATA IMAGES
|
GTX01904 IHC-P Image
IHC-P analysis of human malignant melanoma tissue using GTX01904 MITF antibody [34CA5]. Note nuclear staining of melanoma cells.
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REFERENCE
There are currently no references for MITF antibody [34CA5] (GTX01904). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MITF antibody [34CA5] (GTX01904). Be the first to share your experience with this product.