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MITF antibody [34CA5]

Anti-MITF antibody [34CA5] used in IHC (Paraffin sections) (IHC-P). GTX01904

Cat No. GTX01904

Host

Mouse

Clonality

Monoclonal

Clone Name

34CA5

Isotype

IgG1

Application

IHC-P, IHC-Fr

Reactivity

Human
Package
500 μl ($519)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:10–1:20
IHC-Fr Assay dependent

Note :

IHC-P
High temperature antigen unmasking technique using 1 mM EDTA (pH 8.0). Standard ABC technique.

IHC-Fr
Acetone fixation recommended

Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Product Note

This antibody recognizes human microphthalmia transcription factor, MITF-M isoform.

PROPERTIES

Form

Liquid

Buffer

Tissue culture supernatant

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Prokaryotic recombinant protein corresponding to 111 amino acids of the N-terminal region of the MITF-M molecule.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

melanocyte inducing transcription factor , CMM8 , COMMAD , MI , WS2 , WS2A , bHLHe32

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-MITF antibody [34CA5] used in IHC (Paraffin sections) (IHC-P). GTX01904

GTX01904 IHC-P Image

IHC-P analysis of human malignant melanoma tissue using GTX01904 MITF antibody [34CA5]. Note nuclear staining of melanoma cells.

REFERENCE

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REVIEW

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Package List Price ($)
$ 519