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MITF antibody [C5]

Anti-MITF antibody [C5] used in IHC (Paraffin sections) (IHC-P). GTX12039

Cat. No. GTX12039

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 C5

Isotype

 IgG1

Application

 WB, IHC-P, IHC-Fr, IP, Gel supershift assays

Reactivity

 Human, Mouse, Rat
Package
50 μg ($439)
See all MITF products

APPLICATION

Application Note

For IP: Use at a concentration of 2 μg/ml. For WB: Use at a concentration of 1 μg/ml. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

59 kDa. ( Note )

Positive Control

501 Mel human melanoma cells and wild-type human, rat or mouse osteoclast cells

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.08% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

N-terminal fragment of human microphthalmia protein and mouse myeloma NS1 cells.

Purification

Protein G purified

Conjugation

Unconjugated

RRID

AB_372369

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

melanocyte inducing transcription factor , CMM8 , COMMAD , MI , WS2 , WS2A , bHLHe32

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-MITF antibody [C5] used in IHC (Paraffin sections) (IHC-P). GTX12039

GTX12039 IHC-P Image

Immunohistochemical staining using microphthalmia antibody on formalin fixed, paraffin embedded human melanoma.

REFERENCE

Application Reference

Kawahara K et al. Glia 2016; 64 (11) : 1938-61 the novel monoclonal antibody 9f5 reveals expression of a fragment of gpnmb/osteo* processed by furin-like protease(s) in a subpopulation of microglia in neonatal rat brain.
Application : IHC-Fr
Reactivity : Mouse, Rat
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SDS
Sodium Azide.pdf
Package List Price ($)
$ 439