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MITF antibody [MITF/2987R]

Anti-MITF antibody [MITF/2987R] used in IHC (Paraffin sections) (IHC-P). GTX02674
Anti-MITF antibody [MITF/2987R] used in IHC (Paraffin sections) (IHC-P). GTX02674

Cat No. GTX02674

Host

Rabbit

Clonality

Monoclonal

Clone Name

MITF/2987R

Isotype

IgG

Application

ICC/IF, IHC-P, FACS

Reactivity

Human, Dog
Package
100 μg ($469)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1-2 μg/ml
IHC-P 1-2 μg/ml
FACS 1-2 μg/million cells

Note :

IHC-P
Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris buffer with 1mM EDTA (pH 9.0) for 45 min at 95ºC followed by cooling at RT for 20 minutes.

Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Product Note

This antibody recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanocytes, benign nevi and dysplastic nevi.
We do not recommend use of this product for Mouse,Rat samples.

PROPERTIES

Form

Liquid

Buffer

10mM PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant full-length human MiTF protein

Purification

Protein A/G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

melanocyte inducing transcription factor , CMM8 , COMMAD , MI , WS2 , WS2A , bHLHe32

Cellular Localization

Nucleus

Background

The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-MITF antibody [MITF/2987R] used in IHC (Paraffin sections) (IHC-P). GTX02674

GTX02674 IHC-P Image

IHC-P analysis of human melanoma section using GTX02674 MITF antibody [MITF/2987R].

Anti-MITF antibody [MITF/2987R] used in IHC (Paraffin sections) (IHC-P). GTX02674

GTX02674 IHC-P Image

IHC-P analysis of human melanoma section using GTX02674 MITF antibody [MITF/2987R].

REFERENCE

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REVIEW

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Package List Price ($)
$ 469