This antibody recognizes MiTF-M, MiTF-A, MiTF-C, MiTF-H and other MiTF isoforms.
PROPERTIES
Form
Liquid
Buffer
Serum
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Antigen Species
Human
Immunogen
Recombinant full-size human Mitf (isoform M) protein with His tag
Purification
Unpurified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
The protein encoded by this gene is a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. The encoded protein regulates melanocyte development and is responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. [provided by RefSeq, Aug 2017]
ICC/IF analysis of Mouse primary melanocytes (6 weeks) using GTX00738 MITF antibody. Dilution : 1:500
Show More +
GTX00738 ICC/IF Image
ICC/IF analysis of mouse melanoma B16 cells using GTX00738 MITF antibody. Green : Primary antibody Blue : DAPI Dilution : 1:1000 Fixation : 4% PFA Permeabilization : 0.25 % Triton X-100
Show More +
GTX00738 IHC-Fr Image
IHC-Fr analysis of chick embryo (stage 14, 8 μm) using GTX00738 MITF antibody. At stage 14, Mitif protein is detected throughout the RPE (Retinal Pigment Epithelium). Dilution : 1:300 Fixation : 4% PFA
Show More +
GTX00738 WB Image
WB analysis of various samples using GTX00738 MITF antibody. Untreared : human melanoma cells Control : human melanoma cells treated with control siRNA Mitf : human melanoma cells treated with Mitf siRNA Dilution : 1:1000