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MKL1 antibody

Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556
Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556
Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556
Anti-MKL1 antibody used in Western Blot (WB). GTX64556

Cat. No. GTX64556

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MKL1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

99 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human MKL1 (NP_065882.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

myocardin related transcription factor A , BSAC , MAL , MKL , MKL1 , MRTF-A

Cellular Localization

Cytoplasm,Nucleus

Background

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Database

Research Area

DATA IMAGES

Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556

GTX64556 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX64556 MKL1 antibody.

Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556

GTX64556 IHC-P Image

IHC-P analysis of rat brain tissue using GTX64556 MKL1 antibody.

Anti-MKL1 antibody used in IHC (Paraffin sections) (IHC-P). GTX64556

GTX64556 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX64556 MKL1 antibody.

Anti-MKL1 antibody used in Western Blot (WB). GTX64556

GTX64556 WB Image

WB analysis of various sample lysates using GTX64556 MKL1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399