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MLH1 antibody [IHC409]

Anti-MLH1 antibody [IHC409] used in IHC (Paraffin sections) (IHC-P). GTX57187

Cat. No. GTX57187

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 IHC409

Isotype

 IgG2a

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($399)
See all MLH1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:100-1:200

Note :

IHC-P
Heat-induced epitope retrieval (HIER) at pH 9 for 10 - 30 minutes
Not tested in other applications.

Calculated MW

85 kDa. ( Note )

Positive Control

Colon, Colon Carcinoma

PROPERTIES

Form

Liquid

Buffer

Tris buffer, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human MLH1 protein.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

Mutl Homolog 1 , Coca2 , Fcc2 , Hnpcc , Hnpcc2 , Hmlh1 , Mlh1

Background

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]

Research Area

DATA IMAGES

Anti-MLH1 antibody [IHC409] used in IHC (Paraffin sections) (IHC-P). GTX57187

GTX57187 IHC-P Image

IHC-P analysis of human esophagus tissue using GTX57187 MLH1 antibody [IHC409]

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 399