GeneTex
United States (US)

MLK3 (phospho Thr277/Ser281) antibody

Anti-MLK3 (phospho Thr277/Ser281) antibody used in Western Blot (WB). GTX32300

Cat No. GTX32300

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
Not tested in other applications.

Calculated MW

93 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

0.42% Potassium phosphate, 0.87% Sodium chloride pH 7.3, 30% glycerol, 0.01% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20º C or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of MLK3. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Mitogen-Activated Protein Kinase Kinase Kinase 11,Mekk11,Mlk-3,Mlk3,Ptk1,Sprk,Map3K11

Cellular Localization

Centrosome,Cytoplasm,Cytoskeleton,Microtubule organizing center

Background

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
Anti-MLK3 (phospho Thr277/Ser281) antibody used in Western Blot (WB). GTX32300

GTX32300 WB Image

WB analysis of HEK293T (A), NIH3T3 (B), PC12 (C) whole cell lysates using GTX32300 MLK3 (phospho Thr277/Ser281) antibody.

Package List Price ($)
$ 319