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MLKL antibody

Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in IHC (Paraffin sections) (IHC-P). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807
Anti-MLKL antibody used in Western Blot (WB). GTX03807

Cat. No. GTX03807

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse
Package
200 μl ($399)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
IHC-P 1:400
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

KLH conjugated synthetic peptide between 444-472 amino acids from the C-terminal region of mouse Mlkl.

Purification

Protein A purified followed by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

mixed lineage kinase domain-like , 9130019I15Rik

Cellular Localization

Cytoplasm , Cell membrane

Background

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of various sample lysates using GTX03807 MLKL antibody.
Lane 1 : mouse testis
Lane 2 : mouse liver
Lane3 : NIH-3T3
Dilution : 1:2000
Loading : 20 μg per lane

Anti-MLKL antibody used in IHC (Paraffin sections) (IHC-P). GTX03807

GTX03807 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX03807 MLKL antibody.
Dilution : 1:400

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of various sample lysates using GTX03807 MLKL antibody.
Lane 1 : mouse lung
Lane 2 : NIH/3T3
Lane 3 : mouse liver
Lane 4 : mouse testis
Dilution : 1:2000
Loading : 20 μg per lane

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of mouse lung tissue lysates using GTX03807 MLKL antibody
Dilution : 1:1000
Loading : 20 μg per lane

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of various sample lysates using GTX03807 MLKL antibody.
Lane 1 : NIH-3T3
Lane 2 : mouse spleen
Dilution : 1:2000
Loading : 20 μg per lane

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of mouse spleen tissue lysate using GTX03807 MLKL antibody
Dilution : 1:1000
Loading : 35μg per lane

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of NIH-3T3 cell lysates using GTX03807 MLKL antibody.
Loading : 35μg per lane

Anti-MLKL antibody used in Western Blot (WB). GTX03807

GTX03807 WB Image

WB analysis of mouse lung tissue lysate using GTX03807 MLKL antibody
Dilution : 1:1000
Loading : 20μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 399