APPLICATION
Application Note
ELISA: Use at a concentration of 0.1 - 1.0 μg/ml. IP: Use 3-5μg for 10^6 cells. WB: Use at a concentration of 0.5 - 2.0 μg/ml. Predicted molecular weight: 54 kDa. Optimal dilutions/concentrations should be determined by the end user.
Calculated MW
Product Note
This antibody specifically recognises MMP10, and does not cross-react with MMP1, 2, 3, 7, 8, 9 or 16.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% ProClin
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic peptide (Human).
Purification
Immunogen affinity purified
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
matrix metallopeptidase 10 , SL-2 , STMY2
Background
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down fibronectin, laminin, elastin, proteoglycan core protein, gelatins, and several types of collagen. The gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
Database
Research Area
DATA IMAGES
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GTX25708 WB Image
Western blot analysis of MMP-10 in human MMP-7 over-expressing HEK293 cell lysate probed with GTX25708.
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REFERENCE
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REVIEW
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