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MMP11 antibody

Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717
Anti-MMP11 antibody used in Western Blot (WB). GTX03717
Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717
Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717

Cat. No. GTX03717

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μg ($449)
See all MMP11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.1-0.5μg/ml
IHC-P 0.5-1μg/ml

Note :

IHC-P
Antigen retireval by heat
Not tested in other applications.

Calculated MW

55 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4

Preservative

0.05mg sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MMP11 (104-135aa RWEKTDLTYRILRFPWQLVQEQVRQTMAEALK), different from the related mouse and rat sequences by three amino acids.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 11 , SL-3 , ST3 , STMY3

Cellular Localization

Extracellular matrix

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717

GTX03717 IHC-P Image

IHC-P analysis of human appendicitis tissue using GTX03717 MMP11 antibody.
Antigen retrieval : Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins
Dilution : 1μg/ml

Anti-MMP11 antibody used in Western Blot (WB). GTX03717

GTX03717 WB Image

WB analysis of various cell lysates using GTX03717 MMP11 antibody.
Lane 1 : Rat spleen tissue
Lane 2 : MM231 cell lysate
Dilution : 0.5 μg/mL
Loading : 50 μg per lane

Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717

GTX03717 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX03717 MMP11 antibody.
Antigen retrieval : Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins
Dilution : 1μg/ml

Anti-MMP11 antibody used in IHC (Paraffin sections) (IHC-P). GTX03717

GTX03717 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX03717 MMP11 antibody.
Antigen retrieval : Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins
Dilution : 1μg/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 449