MMP12 ELISA Pair

Cat No. GTX500003

Application	ELISA, Sandwich ELISA
Reactivity	Human
Package	1 pair ($399)

See all MMP12 products

Datasheet

PRODUCT

Product Content

GTX102928

Type : Capture Antibody

Host : Rabbit

Conjugation : Unconjugated

Package : 50 μl

GTX88142

Type : Detection Antibody

Host : Goat

Conjugation : Unconjugated

Package : 50 μl

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Dilution
ELISA	Assay dependent
Sandwich ELISA	Assay dependent

Not tested in other applications.

PROPERTIES

Form

Liquid

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Matrix Metallopeptidase 12 , Hme , Me , Mme , Mmp-12 , Mmp12

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]

Research Area

DATA IMAGES

GTX500003 ELISA Image

ELISA detection of MMP12 using GTX102928 for capture and GTX88142 for detection at a concentration of 0.8-3.2 μg/mL. The HRP-conjugated anti-goat IgG antibody (GTX26741) was diluted at 1:20,000-1:200,000 and used to detect the primary antibody.