*Optimal dilutions/concentrations should be determined by the researcher.
|1:500 - 1:2000
|1:50 - 1:300
Not tested in other applications.
This antibody recognizes human MMP-12 in western blot without cross reactivity with other human MMPs.
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
200 μg/ml (Please refer to the vial label for the specific concentration.)
Human recombinant MMP-12
Protein G purified
From tissue culture supernatant
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
HME , ME , MME , MMP12 , matrix metallopeptidase 12
Secreted,Extracellular space,Extracellular matrix
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]