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MMP12 antibody [7G20]

Anti-MMP12 antibody [7G20] used in IHC (Paraffin sections) (IHC-P). GTX52478

Cat. No. GTX52478

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7G20

Isotype

 IgG2

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MMP12 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:300
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Product Note

This antibody recognizes human MMP-12 in western blot without cross reactivity with other human MMPs.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-12

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

HME , ME , MME , MMP12 , matrix metallopeptidase 12

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-MMP12 antibody [7G20] used in IHC (Paraffin sections) (IHC-P). GTX52478

GTX52478 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52478 MMP12 antibody [7G20].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399