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MMP12 antibody [7G20]

Anti-MMP12 antibody [7G20] used in IHC (Paraffin sections) (IHC-P). GTX52478

Cat No. GTX52478

Host

Mouse

Clonality

Monoclonal

Clone Name

7G20

Isotype

IgG2

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:300
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes human MMP-12 in western blot without cross reactivity with other human MMPs.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-12

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

HME , ME , MME , MMP12 , matrix metallopeptidase 12

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-MMP12 antibody [7G20] used in IHC (Paraffin sections) (IHC-P). GTX52478

GTX52478 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52478 MMP12 antibody [7G20].

REFERENCE

There are currently no references for MMP12 antibody [7G20] (GTX52478). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MMP12 antibody [7G20] (GTX52478). Be the first to share your experience with this product.
SDS
PBS.pdf