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MMP13 antibody

Anti-MMP13 antibody used in IHC (Paraffin sections) (IHC-P). GTX04845
Anti-MMP13 antibody used in IHC (Paraffin sections) (IHC-P). GTX04845
Anti-MMP13 antibody used in Western Blot (WB). GTX04845

Cat. No. GTX04845

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MMP13 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
ICC/IF 1:100-1:500
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human MMP13(Accession P45452), corresponding to amino acid residues H2-L52.

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLG3,MANDP1,MDST,MMP13,matrix metallopeptidase 13

Cellular Localization

Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-MMP13 antibody used in IHC (Paraffin sections) (IHC-P). GTX04845

GTX04845 IHC-P Image

IHC-P analysis of human pancreatic cancer and adjacent normal tissues using GTX04845 MMP13 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-MMP13 antibody used in IHC (Paraffin sections) (IHC-P). GTX04845

GTX04845 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX04845 MMP13 antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-MMP13 antibody used in Western Blot (WB). GTX04845

GTX04845 WB Image

WB analysis of HeLa whole cell lysate using GTX04845 MMP13 antibody. The lane on the right was treated with blocking peptide.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399