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MMP14 antibody [9E10]

Anti-MMP14 antibody [9E10] used in IHC (Paraffin sections) (IHC-P). GTX52480

Cat No. GTX52480

Host

Mouse

Clonality

Monoclonal

Clone Name

9E10

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:400 - 1:800
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes human MMP-14 in western blot without cross reactivity with human MMP-1-13, and MMP14-15.

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-14

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MMP14 , MMPX1 , MT1MMP , MTMMP , MTMMP 1 , MTMMP1 , WNCHRS , matrix metallopeptidase 14

Cellular Localization

Membrane,Melanosome,Cytoplasm

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP14 antibody [9E10] used in IHC (Paraffin sections) (IHC-P). GTX52480

GTX52480 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52480 MMP14 antibody [9E10].

REFERENCE

There are currently no references for MMP14 antibody [9E10] (GTX52480). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MMP14 antibody [9E10] (GTX52480). Be the first to share your experience with this product.
SDS
PBS.pdf