GeneTex
United States (US)

MMP14 antibody

GTX54361_20180530_WB_18121411_159.jpg
GTX54361_20180530_IHC-P_3_18121411_266.jpg
GTX54361_20180530_IHC-P_18121411_303.jpg
GTX54361_20180530_IHC-P_2_18121411_345.jpg
GTX54361_20180530_IHC-P_1_18121411_630.jpg

Cat No. GTX54361

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

66 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant protein of human MMP14

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

MT MMP 1 Antibody , 1 Antibody , MT MMP Antibody , MT1MMP Antibody , MMP X1 Antibody , MTMMP1 Antibody

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX54361_20180530_WB_18121411_159.jpg

GTX54361 WB Image

WB analysis of various samples using GTX54361 MMP14 antibody.
Dilution : 1:1000
Loading : 25μg per lane

GTX54361_20180530_IHC-P_3_18121411_266.jpg

GTX54361 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX54361 MMP14 antibody.
Dilution : 1:100

GTX54361_20180530_IHC-P_18121411_303.jpg

GTX54361 IHC-P Image

IHC-P analysis of human kidney tissue using GTX54361 MMP14 antibody.
Dilution : 1:100

GTX54361_20180530_IHC-P_2_18121411_345.jpg

GTX54361 IHC-P Image

IHC-P analysis of human stomach tissue using GTX54361 MMP14 antibody.
Dilution : 1:100

GTX54361_20180530_IHC-P_1_18121411_630.jpg

GTX54361 IHC-P Image

IHC-P analysis of human liver cancer tissue using GTX54361 MMP14 antibody.
Dilution : 1:100