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MMP14 antibody

Anti-MMP14 antibody used in IHC (Paraffin sections) (IHC-P). GTX54361
Anti-MMP14 antibody used in Western Blot (WB). GTX54361
Anti-MMP14 antibody used in IHC (Paraffin sections) (IHC-P). GTX54361

Cat. No. GTX54361

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all MMP14 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

66 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein of human MMP14

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 14 , MMP-14 , MMP-X1 , MT-MMP , MT-MMP 1 , MT1-MMP , MT1MMP , MTMMP1 , WNCHRS

Cellular Localization

Membrane,Cytoplasm

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP14 antibody used in IHC (Paraffin sections) (IHC-P). GTX54361

GTX54361 IHC-P Image

IHC-P analysis of rat kidney tissue using GTX54361 MMP14 antibody.
Dilution : 1:100

Anti-MMP14 antibody used in Western Blot (WB). GTX54361

GTX54361 WB Image

WB analysis of various sample lysates using GTX54361 MMP14 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-MMP14 antibody used in IHC (Paraffin sections) (IHC-P). GTX54361

GTX54361 IHC-P Image

IHC-P analysis of human kidney tissue using GTX54361 MMP14 antibody.
Dilution : 1:100

REFERENCE

Application Reference

Luis Placido et al. Int J Mol Sci 2021; 22 (6) Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis.
Application : WB, IHC-P
Reactivity : Human
Placido L. et al. Int. J. Mol. Sci. 2021; 22 (6) : 2923 Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis.
Application : WB
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399