GeneTex

  • Country / Location Selection

United States (US)

MMP15 (cleaved Tyr132) antibody

Anti-MMP15 (cleaved Tyr132) antibody used in Western Blot (WB). GTX86936

Cat. No. GTX86936

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Monkey
Package
100 μg ($399)
See all MMP15 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

76 kDa. ( Note )

Product Note

MMP15 (cleaved Tyr132) antibody detects endogenous levels of fragment of activated MMP15 resulting from cleavage adjacent to Tyr132.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human MMP15 (113-162).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MMP15 , MT2MMP , MTMMP2 , SMCP2 , matrix metallopeptidase 15

Cellular Localization

Membrane

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP15 (cleaved Tyr132) antibody used in Western Blot (WB). GTX86936

GTX86936 WB Image

WB analysis of COS7 cells treated with etoposide 25uM 1h using GTX86936 MMP15 (cleaved Tyr132) antibody.

REFERENCE

There are currently no references for MMP15 (cleaved Tyr132) antibody (GTX86936). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for MMP15 (cleaved Tyr132) antibody (GTX86936). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399