MMP17 antibody [N2C2], Internal

Name: MMP17 antibody [N2C2], Internal
Brand: GeneTex
SKU: GTX105268
Price: 419.00 USD
Rating: 4 (1 reviews)

Anti-MMP17 antibody [N2C2], Internal used in IHC (Paraffin sections) (IHC-P). GTX105268

Anti-MMP17 antibody [N2C2], Internal used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX105268

Anti-MMP17 antibody [N2C2], Internal used in Western Blot (WB). GTX105268

Cat. No. GTX105268

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P
Reactivity	Human
Package	100 μl ($419), 25 μl ($169)

See all MMP17 products

Datasheet
Document

View product citations for antibody GTX105268 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	1:500-1:3000
ICC/IF	1:100-1:1000
IHC-P	1:100-1:1500

Not tested in other applications.

Calculated MW

67 kDa. ( Note )

Positive Control

HeLa

Predict Reactivity

Mouse, Rat, Xenopus tropicalis(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA, 20% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.74 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human MMP17. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_2037447

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 17 , MMP-17 , MT4-MMP , MT4MMP , MTMMP4

Cellular Localization

Isoform Long: Cell membrane; Lipid-anchor , GPI-anchor; Extracellular side , Secreted , extracellular space , extracellular matrix

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq]

Database

Gene ID: 4326 MMP17
UniProt: Q9ULZ9 MMP17

Research Area

DATA IMAGES

GTX105268 IHC-P Image

MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol and membrane on human gastric cancer by immunohistochemical analysis.
Sample: Paraffin-embedded gastric cancer.
MMP17 antibody [N2C2], Internal (GTX105268) dilution: 1:500.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX105268 ICC/IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using MMP17(GTX105268) antibody at 1:200 dilution.

GTX105268 IHC-P Image

MMP17 antibody [N2C2], Internal detects MMP17 protein at cytosol on human gastria carcinoma by immunohistochemical analysis.
Sample: Paraffin-embedded human gastria carcinoma.
MMP17 antibody [N2C2], Internal (GTX105268) dilution: 1:1500.
Scale bar = 100 μm.

Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX105268 WB Image

Sample (30 ug of whole cell lysate)
A: Hela
7.5% SDS PAGE
GTX105268 diluted at 1:1000

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REVIEW