APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500~1:1000 |
Not tested in other applications.
Calculated MW
Product Note
MMP17 (cleaved Gln129) antibody detects endogenous levels of fragment of activated MMP17 resulting from cleavage adjacent to Gln129.
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP17 (110-159).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
MMP17 , MT4MMP , MTMMP4 , matrix metallopeptidase 17
Cellular Localization
Cell membrane,Secreted,Extracellular space,Extracellular matrix
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene is considered a member of the membrane-type MMP (MT-MMP) subfamily. However, this protein is unique among the MT-MMP's in that it is a GPI-anchored protein rather than a transmembrane protein. The protein activates MMP-2 by cleavage. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX86926 WB Image
WB analysis of A549 cells treated with etoposide using GTX86926 MMP17 (cleaved Gln129) antibody.
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REFERENCE
There are currently no references for MMP17 (cleaved Gln129) antibody (GTX86926). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MMP17 (cleaved Gln129) antibody (GTX86926). Be the first to share your experience with this product.