Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1,000 |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Product Note
Reacts with reduced and non-reduced MMP-18. Recognizes the pro-form and the active forms of MMP-18. By immunoblotting, the antibody reacts with bands at 53 kDa and 51 kDa (proform).
Form
Liquid
Buffer
PBS, 50% Glycerol
Preservative
15mM Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
~1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Xenopus laevis
Immunogen
synthetic peptide corresponding to the N-terminal of Xenopus matrix metalloproteinase-18 (Xenopus collagenase, collagenase-4)
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
Synonyms
matrix metallopeptidase 19 , CODA , MMP18 , RASI-1
Background
This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Database
Research Area