*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
Reacts with reduced and non-reduced MMP-19. Recognizes the pro-form of MMP-19. Binds the propeptide region, which is removed during activation. Can be used to distinguish between the pro-form and active forms of MMP-19.
0.01M PBS pH7.4, 50% Glycerol
15mM Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
~1 mg/ml (Please refer to the vial label for the specific concentration.)
synthetic peptide corresponding to the propeptide region of human matrix metalloproteinase-19 (RASI).
Purified by affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
matrix metallopeptidase 19 , CODA , MMP18 , RASI-1
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development,reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases.