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MMP2 antibody [2C1]

Anti-MMP2 antibody [2C1] used in Western Blot (WB). GTX27033
Anti-MMP2 antibody [2C1] used in Western Blot (WB). GTX27033
Anti-MMP2 antibody [2C1] used in IHC (Paraffin sections) (IHC-P). GTX27033
Anti-MMP2 antibody [2C1] used in IHC (Paraffin sections) (IHC-P). GTX27033

Cat. No. GTX27033

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2C1

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA

Reactivity

 Human, Mouse, Rat, Guinea pig
Package
50 μl ($399)
See all MMP2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 - 5 μg/ml
ICC/IF 1:10 - 1:500
IHC-P 5 μg/ml
IHC-Fr 5 μg/ml
IP 1:10 - 1:500
ELISA 1 μg/ml
Not tested in other applications.

Calculated MW

74 kDa. ( Note )

Product Note

This antibody is specific for pro and active MMP-2.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Activated recombinant human MMP2. [UniProt# P08253]

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

matrix metallopeptidase 2 , CLG4 , CLG4A , MMP-2 , MMP-II , MONA , TBE-1

Cellular Localization

Membrane,Nucleus,Mitochondrion

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-MMP2 antibody [2C1] used in Western Blot (WB). GTX27033

GTX27033 WB Image

WB analysis of multiple samples using GTX27033 MMP2 antibody [2C1].
Lane 1 : human recombinant mmp-2
Lane 2 : schwann cell

Anti-MMP2 antibody [2C1] used in Western Blot (WB). GTX27033

GTX27033 WB Image

WB analysis of CHO cell overexpressing human mmp-2 protein using GTX27033 MMP2 antibody [2C1].
Dilution : 2 μg/ml

Anti-MMP2 antibody [2C1] used in IHC (Paraffin sections) (IHC-P). GTX27033

GTX27033 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX27033 MMP2 antibody [2C1].
Dilution : 5 μg/ml
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)

Anti-MMP2 antibody [2C1] used in IHC (Paraffin sections) (IHC-P). GTX27033

GTX27033 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX27033 MMP2 antibody [2C1].
Dilution : 5 μg/ml
Antigen retrieval : Heat induced antigen retrieval (HIER) using 10mM sodium citrate buffer (pH 6.0)

REFERENCE

Application Reference

Hongtao Luo et al. Front Public Health 2020; 8 : 579705 Carbon Ion Therapy Inhibits Esophageal Squamous Cell Carcinoma Metastasis by Upregulating STAT3 Through the JAK2/STAT3 Signaling Pathway.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399