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MMP2 antibody

Anti-MMP2 antibody used in Western Blot (WB). GTX27298

Cat No. GTX27298

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP
Reactivity Rat
Package
50μg ($289)
APPLICATION

Application Note

For IP: Use at a dilution of 1:500. For WB: Use at a dilution of 1:2000. Optimal dilutions/concentrations should be determined by the researcher

Calculated MW

74 kDa. ( Note )

Specificity/Sensitivity

MMP2 - No cross-reactivity with other MMP family members.
PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline containing 0.1% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

E. coli-expressed active rat 72-kDa type IV collagenase (catalytic domain)

Purification

Protein A affinity purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Matrix Metallopeptidase 2,Mmp2

Background

The mammalian matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes (ref 1). After cleavage of a signal peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP (ref 2). MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contain the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling.

Database

Research Area

DATA IMAGES
Anti-MMP2 antibody used in Western Blot (WB). GTX27298

GTX27298 WB Image


REFERENCE
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REVIEW
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Package List Price ($)
$ 289