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MMP25 antibody [2B5]

Anti-MMP25 antibody [2B5] used in IHC (Paraffin sections) (IHC-P). GTX52482

Cat No. GTX52482

Host

Mouse

Clonality

Monoclonal

Clone Name

2B5

Isotype

IgG1

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000 - 1:2000
IHC-P 1:50 - 1:500
Not tested in other applications.

Calculated MW

63 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-25

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

MMP20 , MMP20A , MMP25 , MMPL1 , MT6MMP , MTMMP 6 , MTMMP6 , matrix metallopeptidase 25

Cellular Localization

Cell membrane,Secreted,Extracellular space,Extracellular matrix

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily, attached to the plasma membrane via a glycosylphosphatidyl inositol anchor. In response to bacterial infection or inflammation, the encoded protein is thought to inactivate alpha-1 proteinase inhibitor, a major tissue protectant against proteolytic enzymes released by activated neutrophils, facilitating the transendothelial migration of neutrophils to inflammatory sites. The encoded protein may also play a role in tumor invasion and metastasis through activation of MMP2. The gene has previously been referred to as MMP20 but has been renamed MMP25. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-MMP25 antibody [2B5] used in IHC (Paraffin sections) (IHC-P). GTX52482

GTX52482 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52482 MMP25 antibody [2B5].

REFERENCE

There are currently no references for MMP25 antibody [2B5] (GTX52482). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for MMP25 antibody [2B5] (GTX52482). Be the first to share your experience with this product.
SDS
PBS.pdf