APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500~1:1000 |
Not tested in other applications.
Calculated MW
Product Note
MMP3 (cleaved Phe100) antibody detects endogenous levels of fragment of activated MMP3 resulting from cleavage adjacent to Phe100.
PROPERTIES
Form
Liquid
Buffer
PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human MMP3 (81-130).
Purification
Purified by antigen-affinity chromatography
From serum
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
CHDS6 , MMP3 , SL1 , STMY , STMY1 , STR1 , matrix metallopeptidase 3
Cellular Localization
Secreted,Extracellular space,Extracellular matrix
Background
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX86941 WB Image
WB analysis of A549 cells treated with etoposide using GTX86941 MMP3 (cleaved Phe100) antibody.
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REFERENCE
There are currently no references for MMP3 (cleaved Phe100) antibody (GTX86941). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for MMP3 (cleaved Phe100) antibody (GTX86941). Be the first to share your experience with this product.