APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:500 - 1:2000 |
1:50 - 1:200 |
Not tested in other applications.
Calculated MW
Product Note
This antibody recognizes human MMP-7 in western blot without cross reactivity with other human MMPs.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
200 μg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Human recombinant MMP-7
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Unconjugated
RRID
AB_2887803
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
MMP7 , MPSL1 , PUMP1 , matrix metallopeptidase 7
Cellular Localization
Secreted,Extracellular space,Extracellular matrix
Background
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]
Database
Research Area
DATA IMAGES
|
GTX52475 WB Image
WB analysis of SK-OV-3 cell lysates using GTX52475 MMP7 antibody [4C21].
|
|
GTX52475 IHC-P Image
IHC-P analysis of formalin fixed human placenta tissue using GTX52475 MMP7 antibody [4C21].
|
REFERENCE
REVIEW
There are currently no reviews for MMP7 antibody [4C21] (GTX52475). Be the first to share your experience with this product.