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MMP7 antibody, C-term

Anti-MMP7 antibody, C-term used in Western Blot (WB). GTX89487
Anti-MMP7 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89487

Cat No. GTX89487

Host

Goat

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.03-0.1μg/ml
IHC-P 3-6μg/ml

Note :

IHC-P
Human Uterus shows basal staining of an endometrial gland.

Not tested in other applications.

Calculated MW

30 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89487-PEP).

PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-QKLYGKRSNSRKK, from the C Terminus of the protein sequence according to NP_002414.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

matrix metallopeptidase 7 , MMP-7 , MPSL1 , PUMP-1

Background

This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. [provided by RefSeq, Jan 2016]

Database

Research Area

DATA IMAGES

Anti-MMP7 antibody, C-term used in Western Blot (WB). GTX89487

GTX89487 WB Image

WB analysis of human breast lysate using GTX89487 MMP7 antibody, C-term.
Dilution : 0.03μg/ml
Loading : 35μg protein in RIPA buffer

Anti-MMP7 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89487

GTX89487 IHC-P Image

IHC-P analysis of human uterus using GTX89487 MMP7 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8μg/ml

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf