GeneTex
United States (US)

MMP7 antibody

GTX32725_20180530_IHC-P_18121410_177.jpg
GTX32725_20180530_IHC-P_1_18121410_678.jpg
GTX32725_20180530_WB_18121410_723.jpg

Cat No. GTX32725

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

30 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human MMP7 (NP_002414.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Matrix Metallopeptidase 7,Mmp-7,Mpsl1,Pump-1,Mmp7

Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX32725_20180530_IHC-P_18121410_177.jpg

GTX32725 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX32725 MMP7 antibody.
Dilution : 1:100

GTX32725_20180530_IHC-P_1_18121410_678.jpg

GTX32725 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX32725 MMP7 antibody.
Dilution : 1:100

GTX32725_20180530_WB_18121410_723.jpg

GTX32725 WB Image

WB analysis of HT-29 cell lysate using GTX32725 MMP7 antibody.
Dilution : 1:1000
Loading : 25μg per lane