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MMP8 antibody [7A11]

Anti-MMP8 antibody [7A11] used in IHC (Paraffin sections) (IHC-P). GTX52476

Cat. No. GTX52476

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7A11

Isotype

 IgG2

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μg ($399)
See all MMP8 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:400 - 1:1000
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

53 kDa. ( Note )

Product Note

This antibody recognizes human MMP-8 in western blot without cross reactivity with other MMPs.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

200 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant MMP-8

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CLG1 , HNC , MMP8 , PMNLCL , matrix metallopeptidase 8

Cellular Localization

Cytoplasmic granule,Secreted,Extracellular space,Extracellular matrix

Background

This gene encodes a member of the matrix metalloproteinase (MMP) family of proteins. These proteins are involved in the breakdown of extracellular matrix in embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Proteolysis at different sites on this protein results in multiple active forms of the enzyme with distinct N-termini. This protein functions in the degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Database

Research Area

DATA IMAGES

Anti-MMP8 antibody [7A11] used in IHC (Paraffin sections) (IHC-P). GTX52476

GTX52476 IHC-P Image

IHC-P analysis of formalin fixed human placenta tissue using GTX52476 MMP8 antibody [7A11].

REFERENCE

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REVIEW

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SDS
PBS.pdf
Package List Price ($)
$ 399