GeneTex
United States (US)

MP1 antibody

GTX31568_1195_IHC-P_20180221_18121410_231.jpg
GTX31568_2753_WB_20180221_18121410_723.jpg
GTX31568_1196_IHC-P_20180221_18121410_509.jpg

Cat No. GTX31568

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

14 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Brain Tissue Lysate(GTX27918)

Specificity/Sensitivity

At least two isoforms of LAMTOR3 are known to exist; this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

MP1 antibody was raised against an 15 amino acid peptide near the center of human MP1.The immunogen is located within amino acids 40 - 90 of MP1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Late Endosomal/Lysosomal Adaptor, Mapk And Mtor Activator 3,Map2K1Ip1,Mapbp,Mapksp1,Mp1,Pro0633,Ragulator3,Lamtor3

Background

This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES
GTX31568_1195_IHC-P_20180221_18121410_231.jpg

GTX31568 IHC-P Image

IHC-P analysis of human brain tissue using GTX31568 MP1 antibody.
Working concentration : 5 μg/ml

GTX31568_2753_WB_20180221_18121410_723.jpg

GTX31568 WB Image

WB analysis of human brain tissue lysate using GTX31568 MP1 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX31568_1196_IHC-P_20180221_18121410_509.jpg

GTX31568 IHC-P Image

IHC-P analysis of human brain tissue using GTX31568 MP1 antibody.
Working concentration : 20 μg/ml

Package List Price ($)
$ 329